Preferred Name

Sertraline Hydrochloride
Synonyms
Definitions

The hydrochloride salt of sertraline, a synthetic derivative of naphthalenamine with anti-serotoninergic and anti-depressant properties. Sertraline appears to selectively inhibit the neuronal uptake of serotonin, raising serotonin levels in the CNS.

ID

http://purl.obolibrary.org/obo/NCIT_C29451

Accepted_Therapeutic_Use_For

Major depressive disorder; Obsessive-compulsive disorder; Panic disorder; Posttraumatic stress disorder; Premenstrual dysphoric disorder; Social phobia

ALT_DEFINITION

A drug used to treat depression. It is a type of selective serotonin reuptake inhibitor (SSRI).

CAS_Registry

79559-97-0

CHEBI_ID

CHEBI:9124

Chemical_Formula

C17H17Cl2N.HCl

code

C29451

Contributing_Source

CTRP

FDA

definition

The hydrochloride salt of sertraline, a synthetic derivative of naphthalenamine with anti-serotoninergic and anti-depressant properties. Sertraline appears to selectively inhibit the neuronal uptake of serotonin, raising serotonin levels in the CNS.

Display_Name

Sertraline Hydrochloride

FDA_UNII_Code

UTI8907Y6X

Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C61939

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

http://purl.obolibrary.org/obo/NCIT_C176424

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C116978

label

Sertraline Hydrochloride

Legacy Concept Name

Sertraline_Hydrochloride

NCI_Drug_Dictionary_ID

322832

PDQ_Closed_Trial_Search_ID

322832

PDQ_Open_Trial_Search_ID

322832

Preferred_Name

Sertraline Hydrochloride

prefixIRI

NCIT:C29451

prefLabel

Sertraline Hydrochloride

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0600526

subClassOf

http://purl.obolibrary.org/obo/NCIT_C94725

http://purl.obolibrary.org/obo/NCIT_C265

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