loading...| Preferred Name |
Metoprolol Tartrate |
|
| Synonyms |
|
|
| Definitions |
The tartrate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol tartrate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C29255 |
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| CAS_Registry |
56392-17-7 |
|
| Chemical_Formula |
2C15H25NO3.C4H6O6 |
|
| code |
C29255 |
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| Contributing_Source |
CTRP FDA |
|
| definition |
The tartrate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol tartrate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion. |
|
| Display_Name |
Metoprolol Tartrate |
|
| FDA_UNII_Code |
W5S57Y3A5L |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Metoprolol Tartrate |
|
| Legacy Concept Name |
Metoprolol_Tartrate |
|
| NCI_Drug_Dictionary_ID |
809246 |
|
| Preferred_Name |
Metoprolol Tartrate |
|
| prefixIRI |
NCIT:C29255 |
|
| prefLabel |
Metoprolol Tartrate |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0700548 |
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| subClassOf |