loading...| Preferred Name |
Metoprolol Succinate |
|
| Synonyms |
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|
| Definitions |
The succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol succinate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C29254 |
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| CAS_Registry |
98418-47-4 |
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| Chemical_Formula |
2C15H25NO3.C4H6O4 |
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| code |
C29254 |
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| Contributing_Source |
CTRP FDA |
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| definition |
The succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol succinate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion. |
|
| Display_Name |
Metoprolol Succinate |
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| FDA_UNII_Code |
TH25PD4CCB |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Metoprolol Succinate |
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| Legacy Concept Name |
Metoprolol_Succinate |
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| NCI_Drug_Dictionary_ID |
809245 |
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| Preferred_Name |
Metoprolol Succinate |
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| prefixIRI |
NCIT:C29254 |
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| prefLabel |
Metoprolol Succinate |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0724633 |
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| subClassOf |