loading...| Preferred Name | Carcinoid Tumor | |
| Synonyms |
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| Definitions |
A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C2915 |
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| ALT_DEFINITION |
A slow-growing type of tumor usually found in the gastrointestinal system (most often in the appendix), and sometimes in the lungs or other sites. Carcinoid tumors may spread to the liver or other sites in the body, and they may secrete substances such as serotonin or prostaglandins, causing carcinoid syndrome. |
|
| code |
C2915 |
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| Contributing_Source |
CPTAC CTEP CTRP GDC |
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| definition |
A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement. |
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| Display_Name |
Carcinoid Tumor |
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| ICD-O-3_Code |
8240/3 8241/3 |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C168658 http://purl.obolibrary.org/obo/NCIT_C168656 http://purl.obolibrary.org/obo/NCIT_C168657 http://purl.obolibrary.org/obo/NCIT_C168655 http://purl.obolibrary.org/obo/NCIT_C103057 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C102905 http://purl.obolibrary.org/obo/NCIT_C168662 http://purl.obolibrary.org/obo/NCIT_C168661 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C118168 |
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| Is_Value_For_GDC_Property | ||
| label |
Carcinoid Tumor |
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| Legacy Concept Name |
Carcinoid_Tumor |
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| Maps_To |
Benign carcinoid tumor of unspecified site Benign carcinoid tumor of unknown primary site Enterochromaffin cell carcinoid Carcinoid, NOS Carcinoid tumor, NOS Other benign neuroendocrine tumors 8240/3 8241/3 |
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| Neoplastic_Status |
Undetermined |
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| Preferred_Name |
Carcinoid Tumor |
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| prefixIRI |
NCIT:C2915 |
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| prefLabel |
Carcinoid Tumor |
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| Semantic_Type |
Neoplastic Process |
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| UMLS_CUI |
C0007095 |
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| subClassOf |