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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Gatifloxacin | |
| Synonyms |
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| Definitions |
A synthetic 8-methoxyfluoroquinolone with antibacterial activity against a wide range of gram-negative and gram-positive microorganisms. Gatifloxacin exerts its effect through inhibition of DNA gyrase, an enzyme involved in DNA replication, transcription and repair, and inhibition of topoisomerase IV, an enzyme involved in partitioning of chromosomal DNA during bacterial cell division. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C29070 |
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| CAS_Registry |
112811-59-3 180200-66-2
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| CHEBI_ID |
CHEBI:5280
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| Chemical_Formula |
2C19H22FN3O4.3H2O
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| code |
C29070
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| Contributing_Source |
FDA
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|
| definition |
A synthetic 8-methoxyfluoroquinolone with antibacterial activity against a wide range of gram-negative and gram-positive microorganisms. Gatifloxacin exerts its effect through inhibition of DNA gyrase, an enzyme involved in DNA replication, transcription and repair, and inhibition of topoisomerase IV, an enzyme involved in partitioning of chromosomal DNA during bacterial cell division.
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| FDA_UNII_Code |
L4618BD7KJ
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| Has_Salt_Form | ||
| in_subset | ||
| label |
Gatifloxacin
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|
| Legacy Concept Name |
Gatifloxacin
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|
| Preferred_Name |
Gatifloxacin
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|
| prefixIRI |
NCIT:C29070
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| prefLabel |
Gatifloxacin
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| Semantic_Type |
Pharmacologic Substance Antibiotic
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| UMLS_CUI |
C0753645
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| subClassOf |
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