loading...| Preferred Name |
Doxycycline Hyclate |
|
| Synonyms |
|
|
| Definitions |
The hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. Doxycycline hyclate binds reversibly to the 30S ribosomal subunit, possibly to the 50S ribosomal subunit as well, thereby blocking the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C29007 |
|
| ALT_DEFINITION |
A drug used to treat many types of bacterial infections. It stops the growth of bacteria by keeping them from making proteins. It is a type of antibiotic. |
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| CAS_Registry |
24390-14-5 |
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| CHEBI_ID |
CHEBI:34730 |
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| Chemical_Formula |
2C22H24N2O8.C2H6O.2HCl.H2O |
|
| code |
C29007 |
|
| Contributing_Source |
CTRP FDA |
|
| definition |
The hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. Doxycycline hyclate binds reversibly to the 30S ribosomal subunit, possibly to the 50S ribosomal subunit as well, thereby blocking the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. |
|
| Display_Name |
Doxycycline Hyclate |
|
| FDA_UNII_Code |
19XTS3T51U |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 http://purl.obolibrary.org/obo/NCIT_C173381 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Doxycycline Hyclate |
|
| Legacy Concept Name |
Doxycline_Hyclate |
|
| NCI_Drug_Dictionary_ID |
669084 |
|
| PDQ_Closed_Trial_Search_ID |
669084 |
|
| PDQ_Open_Trial_Search_ID |
669084 |
|
| Preferred_Name |
Doxycycline Hyclate |
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| prefixIRI |
NCIT:C29007 |
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| prefLabel |
Doxycycline Hyclate |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
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| UMLS_CUI |
C0058731 |
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| subClassOf |