loading...| Preferred Name |
Cefdinir |
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| Synonyms |
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| Definitions |
A semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefdinir inhibits bacterial septum and cell wall synthesis formation. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C28914 |
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| CAS_Registry |
91832-40-5 |
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| CHEBI_ID |
CHEBI:3485 |
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| Chemical_Formula |
C14H13N5O5S2 |
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| code |
C28914 |
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| Contributing_Source |
FDA |
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| definition |
A semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefdinir inhibits bacterial septum and cell wall synthesis formation. |
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| FDA_UNII_Code |
CI0FAO63WC |
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| in_subset | ||
| label |
Cefdinir |
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| Legacy Concept Name |
Cefdinir |
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| Preferred_Name |
Cefdinir |
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| prefixIRI |
NCIT:C28914 |
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| prefLabel |
Cefdinir |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
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| UMLS_CUI |
C0060405 |
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| subClassOf |