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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Caspofungin | |
| Synonyms |
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| Definitions |
An antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C28910 |
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| CAS_Registry |
162808-62-0
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| CHEBI_ID |
CHEBI:474180
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| Chemical_Formula |
C52H88N10O15
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| code |
C28910
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| Contributing_Source |
FDA
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| definition |
An antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species.
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| FDA_UNII_Code |
F0XDI6ZL63
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| Has_Salt_Form | ||
| in_subset | ||
| label |
Caspofungin
|
|
| Legacy Concept Name |
Caspofungin
|
|
| Preferred_Name |
Caspofungin
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|
| prefixIRI |
NCIT:C28910
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| prefLabel |
Caspofungin
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| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
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| UMLS_CUI |
C0537894
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| subClassOf |
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