loading...| Preferred Name |
Atovaquone |
|
| Synonyms |
|
|
| Definitions |
A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C28838 |
|
| CAS_Registry |
95233-18-4 |
|
| CHEBI_ID |
CHEBI:575568 |
|
| Chemical_Formula |
C22H19ClO3 |
|
| code |
C28838 |
|
| Contributing_Source |
FDA |
|
| definition |
A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death. |
|
| FDA_UNII_Code |
Y883P1Z2LT |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 |
|
| label |
Atovaquone |
|
| Legacy Concept Name |
Atovoquone |
|
| NCI_Drug_Dictionary_ID |
797848 |
|
| PDQ_Closed_Trial_Search_ID |
797848 |
|
| PDQ_Open_Trial_Search_ID |
797848 |
|
| Preferred_Name |
Atovaquone |
|
| prefixIRI |
NCIT:C28838 |
|
| prefLabel |
Atovaquone |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0165603 |
|
| subClassOf |