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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Astemizole | |
| Synonyms |
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| Definitions |
A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. (NCI04) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C28834 |
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| CAS_Registry |
68844-77-9
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| CHEBI_ID |
CHEBI:2896
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| Chemical_Formula |
C28H31FN4O
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| code |
C28834
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| Contributing_Source |
FDA
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|
| definition |
A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. (NCI04)
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| FDA_UNII_Code |
7HU6337315
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| in_subset | ||
| label |
Astemizole
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|
| Legacy Concept Name |
Astemizole
|
|
| Preferred_Name |
Astemizole
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|
| prefixIRI |
NCIT:C28834
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| prefLabel |
Astemizole
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0699606
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| subClassOf |
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