Preferred Name |
Astemizole |
|
Synonyms |
|
|
Definitions |
A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. (NCI04) |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C28834 |
|
CAS_Registry |
68844-77-9 |
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CHEBI_ID |
CHEBI:2896 |
|
Chemical_Formula |
C28H31FN4O |
|
code |
C28834 |
|
Contributing_Source |
FDA |
|
definition |
A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. (NCI04) |
|
FDA_UNII_Code |
7HU6337315 |
|
in_subset | ||
label |
Astemizole |
|
Legacy Concept Name |
Astemizole |
|
Preferred_Name |
Astemizole |
|
prefixIRI |
NCIT:C28834 |
|
prefLabel |
Astemizole |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0699606 |
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subClassOf |