Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Camptothecin Analogue
Synonyms
Definitions

Any substance based on the structure of camptothecin that stabilizes topoisomerase I-DNA covalent complexes, thereby causing DNA damage and apoptosis.
ID

http://purl.obolibrary.org/obo/NCIT_C2843
ALT_DEFINITION

An anticancer drug related in structure to camptothecin, a topoisomerase inhibitor. One such drug is aminocamptothecin.
code

C2843
definition

Any substance based on the structure of camptothecin that stabilizes topoisomerase I-DNA covalent complexes, thereby causing DNA damage and apoptosis.
label

Camptothecin Analogue
Legacy Concept Name

Camptothecin_Analogue
Preferred_Name

Camptothecin Analogue
prefixIRI

NCIT:C2843
prefLabel

Camptothecin Analogue
Semantic_Type

Chemical Viewed Structurally
UMLS_CUI

C1516155
subClassOf

http://purl.obolibrary.org/obo/NCIT_C1904
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