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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Modafinil | |
| Synonyms |
|
|
| Definitions |
A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C26661 |
|
| Accepted_Therapeutic_Use_For |
Narcolepsy
|
|
| ALT_DEFINITION |
A drug that is being studied as a treatment for fatigue in patients with cancer. It belongs to the family of drugs called stimulants.
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|
| CAS_Registry |
68693-11-8
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|
| Chemical_Formula |
C15H15NO2S
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|
| code |
C26661
|
|
| Contributing_Source |
CTRP FDA
|
|
| definition |
A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04)
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|
| Display_Name |
Modafinil
|
|
| FDA_UNII_Code |
R3UK8X3U3D
|
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Modafinil
|
|
| Legacy Concept Name |
Modafinil
|
|
| NCI_Drug_Dictionary_ID |
256449
|
|
| PDQ_Closed_Trial_Search_ID |
256449
|
|
| PDQ_Open_Trial_Search_ID |
256449
|
|
| Preferred_Name |
Modafinil
|
|
| prefixIRI |
NCIT:C26661
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|
| prefLabel |
Modafinil
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|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0066677
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|
| subClassOf |
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