loading...| Preferred Name | Liothyronine Sodium | |
| Synonyms |
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| Definitions |
The sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4). |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C2581 |
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| ALT_DEFINITION |
A drug that is used to treat certain thyroid (a gland located near the voice box) conditions. It is also being studied in the treatment of thyroid cancer. Cytomel is made in the laboratory and is a form of the thyroid hormone triiodthyronine (T3). |
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| CAS_Registry |
55-06-1 |
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| CHEBI_ID |
CHEBI:6484 |
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| Chemical_Formula |
C15H11I3NO4.Na |
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| code |
C2581 |
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| Contributing_Source |
CTRP FDA |
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| definition |
The sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4). |
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| Display_Name |
Liothyronine Sodium |
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| FDA_UNII_Code |
GCA9VV7D2N |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 http://purl.obolibrary.org/obo/NCIT_C173381 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 |
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| Is_Value_For_GDC_Property | ||
| label |
Liothyronine Sodium |
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| Legacy Concept Name |
Liothyronine_Sodium |
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| Maps_To |
Liothyronine Sodium |
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| NCI_Drug_Dictionary_ID |
43629 |
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| PDQ_Closed_Trial_Search_ID |
43629 |
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| PDQ_Open_Trial_Search_ID |
43629 |
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| Preferred_Name |
Liothyronine Sodium |
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| prefixIRI |
NCIT:C2581 |
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| prefLabel |
Liothyronine Sodium |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance |
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| UMLS_CUI |
C0546882 |
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| subClassOf |