loading...| Preferred Name |
Interferon Alfa-N1 |
|
| Synonyms |
|
|
| Definitions |
A highly purified alpha interferon produced by a human lymphoid cell line. Interferon alpha-n1 consists of multiple alpha interferon subtypes, at least two of which are glycosylated. In contrast, recombinant alpha interferons are individual non-glycosylated proteins produced from individual alpha interferon genes. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose proteins have antiviral, antiproliferative, anticancer, and immune-modulating effects. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C2220 |
|
| Accepted_Therapeutic_Use_For |
Chronic Hepatitis C |
|
| CAS_Registry |
308067-63-2 |
|
| code |
C2220 |
|
| Contributing_Source |
FDA |
|
| definition |
A highly purified alpha interferon produced by a human lymphoid cell line. Interferon alpha-n1 consists of multiple alpha interferon subtypes, at least two of which are glycosylated. In contrast, recombinant alpha interferons are individual non-glycosylated proteins produced from individual alpha interferon genes. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose proteins have antiviral, antiproliferative, anticancer, and immune-modulating effects. (NCI04) |
|
| FDA_UNII_Code |
41697D4Z5C |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C128784 |
|
| Is_Value_For_GDC_Property | ||
| label |
Interferon Alfa-N1 |
|
| Legacy Concept Name |
Interferon_Alfa-N1 |
|
| Maps_To |
Interferon Alfa-N1 |
|
| NSC Number |
339140 |
|
| Preferred_Name |
Interferon Alfa-N1 |
|
| prefixIRI |
NCIT:C2220 |
|
| prefLabel |
Interferon Alfa-N1 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance |
|
| UMLS_CUI |
C0699817 |
|
| subClassOf |