Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Phosphatidylinositide 3-Kinase Inhibitor
Synonyms
Definitions

Any substance that inhibits phosphatidylinositol 3-kinase (phosphatidylinositide 3-kinase), an enzyme that catalyzes the phosphorylation of the 3 position hydroxyl group of the inositol ring of phosphatidylinositol and functions as an intracellular signal transducer in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. Inhibition of phosphatidylinositol 3-kinase produces antiproliferative and antiangiogenic effects.
ID

http://purl.obolibrary.org/obo/NCIT_C2152
CHEBI_ID

CHEBI:50914
code

C2152
Contributing_Source

CTRP
definition

Any substance that inhibits phosphatidylinositol 3-kinase (phosphatidylinositide 3-kinase), an enzyme that catalyzes the phosphorylation of the 3 position hydroxyl group of the inositol ring of phosphatidylinositol and functions as an intracellular signal transducer in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. Inhibition of phosphatidylinositol 3-kinase produces antiproliferative and antiangiogenic effects.
Display_Name

PI3K Inhibitor
Has_Target

http://purl.obolibrary.org/obo/NCIT_C17270
in_subset

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C116978
label

Phosphatidylinositide 3-Kinase Inhibitor
Legacy Concept Name

Phosphatidylinositide_3-Kinase_Inhibitor
Preferred_Name

Phosphatidylinositide 3-Kinase Inhibitor
prefixIRI

NCIT:C2152
prefLabel

Phosphatidylinositide 3-Kinase Inhibitor
Semantic_Type

Chemical Viewed Functionally
UMLS_CUI

C1519050
subClassOf

http://purl.obolibrary.org/obo/NCIT_C163758

http://purl.obolibrary.org/obo/NCIT_C1742

http://purl.obolibrary.org/obo/NCIT_C1404
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