Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Ornithine Decarboxylase Inhibitor
Synonyms
Definitions

Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction in polyamine synthesis. Polyamines are important for stabilizing DNA structure, for the DNA double strand-break repair pathway, and as antioxidants, and inhibition of ornithine decarboxylase inhibits cell growth.
ID

http://purl.obolibrary.org/obo/NCIT_C2088
code

C2088
definition

Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction in polyamine synthesis. Polyamines are important for stabilizing DNA structure, for the DNA double strand-break repair pathway, and as antioxidants, and inhibition of ornithine decarboxylase inhibits cell growth.
label

Ornithine Decarboxylase Inhibitor
Legacy Concept Name

Ornithine_Decarboxylase_Inhibitor
Preferred_Name

Ornithine Decarboxylase Inhibitor
prefixIRI

NCIT:C2088
prefLabel

Ornithine Decarboxylase Inhibitor
Semantic_Type

Chemical Viewed Functionally
UMLS_CUI

C1518618
subClassOf

http://purl.obolibrary.org/obo/NCIT_C471

http://purl.obolibrary.org/obo/NCIT_C2076
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