loading...| Preferred Name | Polyamine Synthesis Inhibitor | |
| Synonyms |
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| Definitions |
A compound that inhibits the synthesis of the naturally occurring polyamines, intracellular compounds that bind to DNA and play a critical role in cell division, differentiation and membrane function. These inhibitors affect the activity of enzymes like ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMD) that are involved in the biosynthesis of polyamines. A reduction in intracellular polyamine concentration may lead to a decreased cell growth. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C2076 |
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| code |
C2076 |
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| definition |
A compound that inhibits the synthesis of the naturally occurring polyamines, intracellular compounds that bind to DNA and play a critical role in cell division, differentiation and membrane function. These inhibitors affect the activity of enzymes like ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMD) that are involved in the biosynthesis of polyamines. A reduction in intracellular polyamine concentration may lead to a decreased cell growth. |
|
| label |
Polyamine Synthesis Inhibitor |
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| Legacy Concept Name |
Polyamine_Inhibitory_Agent |
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| Preferred_Name |
Polyamine Synthesis Inhibitor |
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| prefixIRI |
NCIT:C2076 |
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| prefLabel |
Polyamine Synthesis Inhibitor |
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| Semantic_Type |
Chemical Viewed Functionally |
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| UMLS_CUI |
C1514194 |
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| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2076 | NCIT | LOOM |