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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Recombinant Interferon Alfa-2b | |
| Synonyms |
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| Definitions |
A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C1953 |
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| ALT_DEFINITION |
A drug used to treat some infections caused by viruses and several types of cancer. These include hairy cell leukemia, melanoma, and follicular lymphoma. It is a form of interferon alfa (a substance normally made by cells of the immune system) that is made in the laboratory. It is a type of biological response modifier.
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| CAS_Registry |
98530-12-2 99210-65-8
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| code |
C1953
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| Contributing_Source |
CTRP FDA
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| definition |
A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects.
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| Display_Name |
Recombinant Interferon Alfa-2b
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| FDA_UNII_Code |
43K1W2T1M6
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| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 http://purl.obolibrary.org/obo/NCIT_C173381 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Recombinant Interferon Alfa-2b
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| Legacy Concept Name |
Recombinant_Interferon_Alfa-2b
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| Maps_To |
Recombinant Interferon Alfa-2b
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| NCI_Drug_Dictionary_ID |
462279
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| NSC Number |
377523
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| PDQ_Closed_Trial_Search_ID |
462279
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| PDQ_Open_Trial_Search_ID |
462279
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| Preferred_Name |
Recombinant Interferon Alfa-2b
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| prefixIRI |
NCIT:C1953
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| prefLabel |
Recombinant Interferon Alfa-2b
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| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance
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| UMLS_CUI |
C0021735
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| subClassOf |
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| Mapping To | Ontology | Source |
|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1953 | NCIT | LOOM |
| http://purl.bioontology.org/ontology/PDQ/CDR0000462279 | PDQ | LOOM |