loading...| Preferred Name |
Valdecoxib |
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| Synonyms |
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|
| Definitions |
A sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C1869 |
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| Accepted_Therapeutic_Use_For |
Osteoarthritis; rheumatoid arthritis; dysmenorrhea |
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| ALT_DEFINITION |
A substance that is being studied as a treatment for pain and other side effects of cancer therapy. It belongs to the family of drugs called COX-2 inhibitors. |
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| CAS_Registry |
181695-72-7 |
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| CHEBI_ID |
CHEBI:63634 |
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| Chemical_Formula |
C16H14N2O3S |
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| code |
C1869 |
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| Contributing_Source |
FDA |
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| definition |
A sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation. |
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| FDA_UNII_Code |
2919279Q3W |
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| in_subset | ||
| label |
Valdecoxib |
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| Legacy Concept Name |
Valdecoxib |
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| NCI_Drug_Dictionary_ID |
38320 |
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| PDQ_Closed_Trial_Search_ID |
38320 |
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| PDQ_Open_Trial_Search_ID |
38320 |
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| Preferred_Name |
Valdecoxib |
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| prefixIRI |
NCIT:C1869 |
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| prefLabel |
Valdecoxib |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0913246 |
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| subClassOf |