loading...| Preferred Name |
Micafungin |
|
| Synonyms |
|
|
| Definitions |
A semi-synthetic echinocandin derived from a natural product of the fungus Coleophama empedri with potent antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for fungal cell wall synthesis. Inhibition of this enzyme weakens of the cell wall, thereby leading to osmotic lysis and eventually, fungal cell death. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1850 |
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| ALT_DEFINITION |
An antibiotic/antifungal drug used to treat infection. |
|
| CAS_Registry |
235114-32-6 |
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| CHEBI_ID |
CHEBI:600520 |
|
| Chemical_Formula |
C56H71N9O23S |
|
| code |
C1850 |
|
| Contributing_Source |
CTRP FDA |
|
| definition |
A semi-synthetic echinocandin derived from a natural product of the fungus Coleophama empedri with potent antifungal activity. Micafungin, like other cyclic lipopeptides, noncompetitively inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, an enzyme essential for fungal cell wall synthesis. Inhibition of this enzyme weakens of the cell wall, thereby leading to osmotic lysis and eventually, fungal cell death. |
|
| Display_Name |
Micafungin |
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| FDA_UNII_Code |
R10H71BSWG |
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| Has_Salt_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Micafungin |
|
| Legacy Concept Name |
Micafungin |
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| NCI_Drug_Dictionary_ID |
43552 |
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| PDQ_Closed_Trial_Search_ID |
43552 |
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| PDQ_Open_Trial_Search_ID |
43552 |
|
| Preferred_Name |
Micafungin |
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| prefixIRI |
NCIT:C1850 |
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| prefLabel |
Micafungin |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance Antibiotic |
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| UMLS_CUI |
C1120386 |
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| subClassOf |