loading...| Preferred Name |
Nuclear Receptor |
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| Synonyms |
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| Definitions |
Proteins that regulate transcription via interaction with chromatin and basal transcription machinery at the promoter regions of genes. Nuclear receptors are ligand-dependent transcription factors including steroids, retinoids, vitamin D, unliganded thyroid hormone, and orphan receptors (unknown ligands). Coregulators (coactivators or corepressors) are important in mediating these interactions and thereby modulate positive or negative receptor activity. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C17671 |
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| code |
C17671 |
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| definition |
Proteins that regulate transcription via interaction with chromatin and basal transcription machinery at the promoter regions of genes. Nuclear receptors are ligand-dependent transcription factors including steroids, retinoids, vitamin D, unliganded thyroid hormone, and orphan receptors (unknown ligands). Coregulators (coactivators or corepressors) are important in mediating these interactions and thereby modulate positive or negative receptor activity. |
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| label |
Nuclear Receptor |
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| Legacy Concept Name |
Nuclear_Receptor |
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| Preferred_Name |
Nuclear Receptor |
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| prefixIRI |
NCIT:C17671 |
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| prefLabel |
Nuclear Receptor |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Receptor |
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| UMLS_CUI |
C0206588 |
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| subClassOf |