loading...| Preferred Name |
Tumor Progression |
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| Synonyms |
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| Definitions |
A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of a neoplasm. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C17609 |
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| code |
C17609 |
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| Contributing_Source |
CPTAC GDC |
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| definition |
A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of a neoplasm. |
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| DesignNote |
The process of tumor progression is thought to be driven by clonal evolution. The initiating event is a mutation that gives a cell the ability to divide when it shouldn't. As a result a small group of related cells, called a clone because they are identical to each other, grows. Clonal evolution occurs like a tree with mutations causing many clones to branch off continuously. |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C159328 http://purl.obolibrary.org/obo/NCIT_C156952 |
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| Is_Value_For_GDC_Property | ||
| label |
Tumor Progression |
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| Legacy Concept Name |
Tumor_Progression |
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| Maps_To |
Progression |
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| Preferred_Name |
Tumor Progression |
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| prefixIRI |
NCIT:C17609 |
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| prefLabel |
Tumor Progression |
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| Semantic_Type |
Pathologic Function |
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| UMLS_CUI |
C0178874 |
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| subClassOf |