loading...| Preferred Name |
Troponin I |
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| Synonyms |
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| Definitions |
Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. In the absence of calcium, Troponin I binds actin, inhibits actomyosin ATPase activity, and inhibits F-actin-myosin interactions. The troponin I gene family comprises three isoforms: skeletal TNI-fast, skeletal TNI-slow, and TNI-cardiac. (from OMIM 191044, 191043, 191042 and NCI) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C17343 |
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| code |
C17343 |
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| Contributing_Source |
CTRP |
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| definition |
Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. In the absence of calcium, Troponin I binds actin, inhibits actomyosin ATPase activity, and inhibits F-actin-myosin interactions. The troponin I gene family comprises three isoforms: skeletal TNI-fast, skeletal TNI-slow, and TNI-cardiac. (from OMIM 191044, 191043, 191042 and NCI) |
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| Display_Name |
Troponin I |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Troponin I |
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| Legacy Concept Name |
Troponin-I |
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| Preferred_Name |
Troponin I |
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| prefixIRI |
NCIT:C17343 |
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| prefLabel |
Troponin I |
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| Semantic_Type |
Amino Acid, Peptide, or Protein |
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| UMLS_CUI |
C0077401 |
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| subClassOf |