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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Caspofungin Acetate | |
| Synonyms |
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| Definitions |
The acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1724 |
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| ALT_DEFINITION |
A drug used to prevent or treat infections caused by a fungus (a type of microorganism). It belongs to the family of drugs called antifungal agents.
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| CAS_Registry |
179463-17-3
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| CHEBI_ID |
CHEBI:59900
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| Chemical_Formula |
C52H88N10O15.2C2H4O2
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|
| code |
C1724
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| Contributing_Source |
CTRP FDA
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|
| definition |
The acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species.
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| Display_Name |
Caspofungin Acetate
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| FDA_UNII_Code |
VUW370O5QE
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Caspofungin Acetate
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|
| Legacy Concept Name |
Caspofungin_Acetate
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| NCI_Drug_Dictionary_ID |
38182
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| PDQ_Closed_Trial_Search_ID |
38182
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| PDQ_Open_Trial_Search_ID |
38182
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| Preferred_Name |
Caspofungin Acetate
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|
| prefixIRI |
NCIT:C1724
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| prefLabel |
Caspofungin Acetate
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| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
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| UMLS_CUI |
C0935942
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| subClassOf |
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