loading...| Preferred Name |
Insulin Receptor |
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| Synonyms |
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| Definitions |
Insulin receptor (1382 aa, ~156 kDa) is encoded by the human INSR gene. This protein plays a role in both signal transduction and glucose homeostasis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C17072 |
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| code |
C17072 |
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| Contributing_Source |
CTRP |
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| definition |
Insulin receptor (1382 aa, ~156 kDa) is encoded by the human INSR gene. This protein plays a role in both signal transduction and glucose homeostasis. |
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| DesignNote |
Insulin receptor is cleaved to generate and alpha chain and a beta chain. The mature receptor is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. (UniProt) |
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| Display_Name |
Insulin Receptor |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Insulin Receptor |
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| Legacy Concept Name |
Insulin_Receptor |
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| OMIM_Number |
147670 |
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| Preferred_Name |
Insulin Receptor |
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| prefixIRI |
NCIT:C17072 |
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| prefLabel |
Insulin Receptor |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme Receptor |
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| Swiss_Prot |
P06213 |
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| UMLS_CUI |
C1448132 |
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| subClassOf |