Preferred Name |
Voriconazole |
|
Synonyms |
|
|
Definitions |
A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04) |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C1707 |
|
Accepted_Therapeutic_Use_For |
Aspergillosis, invasive; Esophageal candidiasis; Fungal infections, non-aspergillosis |
|
ALT_DEFINITION |
A drug that treats infections caused by fungi. |
|
CAS_Registry |
137234-62-9 |
|
CHEBI_ID |
CHEBI:10023 |
|
Chemical_Formula |
C16H14F3N5O |
|
code |
C1707 |
|
Contributing_Source |
CTRP FDA |
|
definition |
A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04) |
|
Display_Name |
Voriconazole |
|
FDA_UNII_Code |
JFU09I87TR |
|
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
label |
Voriconazole |
|
Legacy Concept Name |
Voriconazole |
|
NCI_Drug_Dictionary_ID |
42690 |
|
PDQ_Closed_Trial_Search_ID |
42690 |
|
PDQ_Open_Trial_Search_ID |
42690 |
|
Preferred_Name |
Voriconazole |
|
prefixIRI |
NCIT:C1707 |
|
prefLabel |
Voriconazole |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic |
|
UMLS_CUI |
C0393080 |
|
subClassOf |