Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
Jump to:
| Preferred Name | Voriconazole | |
| Synonyms |
|
|
| Definitions |
A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1707 |
|
| Accepted_Therapeutic_Use_For |
Aspergillosis, invasive; Esophageal candidiasis; Fungal infections, non-aspergillosis
|
|
| ALT_DEFINITION |
A drug that treats infections caused by fungi.
|
|
| CAS_Registry |
137234-62-9
|
|
| CHEBI_ID |
CHEBI:10023
|
|
| Chemical_Formula |
C16H14F3N5O
|
|
| code |
C1707
|
|
| Contributing_Source |
CTRP FDA
|
|
| definition |
A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04)
|
|
| Display_Name |
Voriconazole
|
|
| FDA_UNII_Code |
JFU09I87TR
|
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Voriconazole
|
|
| Legacy Concept Name |
Voriconazole
|
|
| NCI_Drug_Dictionary_ID |
42690
|
|
| PDQ_Closed_Trial_Search_ID |
42690
|
|
| PDQ_Open_Trial_Search_ID |
42690
|
|
| Preferred_Name |
Voriconazole
|
|
| prefixIRI |
NCIT:C1707
|
|
| prefLabel |
Voriconazole
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Antibiotic
|
|
| UMLS_CUI |
C0393080
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping