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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Insulin-Like Growth Factor II | |
| Synonyms |
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| Definitions |
Insulin-like growth factor II (180 aa, ~20 kDa) is encoded by the human IGF2 gene. This protein plays a role in cellular growth, development, and mitogenesis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C16744 |
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| code |
C16744
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| Contributing_Source |
CTRP
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| definition |
Insulin-like growth factor II (180 aa, ~20 kDa) is encoded by the human IGF2 gene. This protein plays a role in cellular growth, development, and mitogenesis.
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| DesignNote |
Similar to insulin, the full length insulin-like growth factor II precursor protein is cleaved at positions 24 or 25 and at positions 91 and 180 to release a 67 or 66 amino acid growth factor and an 89 amino acid E peptide. The E peptide can be further processed to release prepeptin. (UniProt)
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| Display_Name |
Insulin-Like Growth Factor II
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Insulin-Like Growth Factor II
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| Legacy Concept Name |
Insulin-Like_Growth_Factor-2
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| OMIM_Number |
147470
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| Preferred_Name |
Insulin-Like Growth Factor II
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| prefixIRI |
NCIT:C16744
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| prefLabel |
Insulin-Like Growth Factor II
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| Semantic_Type |
Amino Acid, Peptide, or Protein
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| Swiss_Prot |
P01344
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| UMLS_CUI |
C1569730
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| subClassOf |
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