Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Recombinant Human Stem Cell Factor
Synonyms
Definitions

A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures.
ID

http://purl.obolibrary.org/obo/NCIT_C1410
code

C1410
definition

A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures.
in_subset

http://purl.obolibrary.org/obo/NCIT_C176424
label

Recombinant Human Stem Cell Factor
Legacy Concept Name

Therapeutic_Stem_Cell_Factor
NCI_Drug_Dictionary_ID

41929
PDQ_Closed_Trial_Search_ID

41929
PDQ_Open_Trial_Search_ID

41929
Preferred_Name

Recombinant Human Stem Cell Factor
prefixIRI

NCIT:C1410
prefLabel

Recombinant Human Stem Cell Factor
Semantic_Type

Amino Acid, Peptide, or Protein

Pharmacologic Substance
UMLS_CUI

C1526982
subClassOf

http://purl.obolibrary.org/obo/NCIT_C387
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