Preferred Name

Lysosome

Synonyms
Definitions

A class of morphologically heterogeneous cytoplasmic membrane-bound vesicle in animal and plant tissues characterized by their content of a wide variety of glycoprotein hydrolytic enzymes active at an acid pH and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture serves to digest exogenous material, such as bacteria, as well as effete organelles of the cells and is supposed to be under metabolic (hormonal) control.

ID

http://purl.obolibrary.org/obo/NCIT_C13253

ALT_DEFINITION

A sac-like compartment inside a cell that has enzymes that can break down cellular components that need to be destroyed.

code

C13253

definition

A class of morphologically heterogeneous cytoplasmic membrane-bound vesicle in animal and plant tissues characterized by their content of a wide variety of glycoprotein hydrolytic enzymes active at an acid pH and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture serves to digest exogenous material, such as bacteria, as well as effete organelles of the cells and is supposed to be under metabolic (hormonal) control.

label

Lysosome

Legacy Concept Name

Lysosome

Preferred_Name

Lysosome

prefixIRI

NCIT:C13253

prefLabel

Lysosome

Semantic_Type

Cell Component

UMLS_CUI

C0024369

subClassOf

http://purl.obolibrary.org/obo/NCIT_C33089

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/GO_0005764 GO-PLUS LOOM
http://purl.obolibrary.org/obo/GO_0005764 EFO LOOM
http://purl.obolibrary.org/obo/GO_0005764 UBERON LOOM
http://purl.obolibrary.org/obo/GO_0005764 OBA LOOM
http://purl.obolibrary.org/obo/GO_0005764 GO LOOM
http://purl.obolibrary.org/obo/GO_0005764 ZP LOOM
http://purl.org/obo/owlapi/fma#FMA_63836 BIOMODELS LOOM
http://www.semanticweb.org/ontologies/2008/8/MultiscaleSkinPhysiologyOntology.owl#Lysosome SPO LOOM
http://ccdb.ucsd.edu/SAO/1.2#sao585356902 SAO LOOM
http://www.co-ode.org/ontologies/galen#Lysosome GALEN LOOM
http://scai.fraunhofer.de/AlzheimerOntology#Lysosomes ADO LOOM
http://purl.obolibrary.org/obo/PLANA_0007518 PLANA LOOM
http://purl.obolibrary.org/obo/PLANA_0007518 PLANP LOOM
http://purl.bioontology.org/ontology/LNC/LP71706-3 LOINC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00053937 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0024369 OCHV LOOM
http://purl.obolibrary.org/obo/GO_0005764 NIGO LOOM
http://purl.obolibrary.org/obo/GO_0005764 GO-EXT LOOM
http://purl.obolibrary.org/obo/GO_0005764 CLO LOOM
http://purl.obolibrary.org/obo/GO_0005764 PLANP LOOM
http://purl.obolibrary.org/obo/GO_0005764 CCO LOOM
http://purl.obolibrary.org/obo/GO_0005764 REXO LOOM
http://purl.obolibrary.org/obo/GO_0005764 GEXO LOOM
http://purl.obolibrary.org/obo/GO_0005764 PHAGE LOOM
http://purl.obolibrary.org/obo/GO_0005764 PCL LOOM
http://purl.obolibrary.org/obo/GO_0005764 BAO LOOM
http://purl.obolibrary.org/obo/GO_0005764 NIFDYS LOOM
http://purl.obolibrary.org/obo/GO_0005764 HHEAR LOOM
http://purl.obolibrary.org/obo/GO_0005764 TXPO LOOM
http://purl.obolibrary.org/obo/GO_0005764 UPHENO LOOM
http://purl.obolibrary.org/obo/GO_0005764 NIFSTD LOOM
http://purl.obolibrary.org/obo/GO_0005764 KTAO LOOM
http://purl.obolibrary.org/obo/GO_0005764 REGN_GO LOOM
http://purl.obolibrary.org/obo/GO_0005764 RETO LOOM
http://purl.obolibrary.org/obo/GO_0005764 MAXO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13253 NCIT LOOM
http://purl.jp/bio/4/id/200906003246483626 IOBC LOOM
http://purl.bioontology.org/ontology/CSP/0596-5505 CRISP LOOM
http://purl.org/sig/ont/fma/fma63836 FMA LOOM
http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Subcellular.owl#sao585356902 NIFSUBCELL LOOM
http://uri.neuinfo.org/nif/nifstd/sao585356902 NIFSTD LOOM
http://purl.org/obo/owl/GO#GO_0005764 BIOMODELS LOOM
http://www.projecthalo.com/aura#Lysosome AURA LOOM
http://www.semanticweb.org/ADMO#c19 ADMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/52971004 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/GO_0005764 CL LOOM
http://purl.obolibrary.org/obo/GO_0005764 HOIP LOOM