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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Vortioxetine Hydrobromide | |
| Synonyms |
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| Definitions |
A hydrobromide salt form of vortioxetine, a serotonin (5-HT) modulator and stimulator (SMS), with antidepressant activity. Vortioxetine inhibits the reuptake of serotonin and norepinephrine from the synaptic cleft and acts variably as a serotonin receptor agonist (5-HT1A), partial agonist (5-HT1B) or antagonist (5-HT3, 5-HT1D and 5-HT7). It is not clear how this agent's purported multimodal mechanism of action contributes to its antidepressant effect; however, it is presumed to increase the synaptic availability of serotonin and norepinephrine. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C125653 |
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| CAS_Registry |
960203-27-4
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| code |
C125653
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| Contributing_Source |
FDA
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| definition |
A hydrobromide salt form of vortioxetine, a serotonin (5-HT) modulator and stimulator (SMS), with antidepressant activity. Vortioxetine inhibits the reuptake of serotonin and norepinephrine from the synaptic cleft and acts variably as a serotonin receptor agonist (5-HT1A), partial agonist (5-HT1B) or antagonist (5-HT3, 5-HT1D and 5-HT7). It is not clear how this agent's purported multimodal mechanism of action contributes to its antidepressant effect; however, it is presumed to increase the synaptic availability of serotonin and norepinephrine.
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| FDA_UNII_Code |
TKS641KOAY
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| in_subset | ||
| label |
Vortioxetine Hydrobromide
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| NCI_Drug_Dictionary_ID |
778329
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| PDQ_Closed_Trial_Search_ID |
778329
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| PDQ_Open_Trial_Search_ID |
778329
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| Preferred_Name |
Vortioxetine Hydrobromide
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| prefixIRI |
NCIT:C125653
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| prefLabel |
Vortioxetine Hydrobromide
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| Semantic_Type |
Organic Chemical Pharmacologic Substance
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| UMLS_CUI |
C3667599
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| subClassOf |
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