Preferred Name

Vortioxetine Hydrobromide

Synonyms
Definitions

A hydrobromide salt form of vortioxetine, a serotonin (5-HT) modulator and stimulator (SMS), with antidepressant activity. Vortioxetine inhibits the reuptake of serotonin and norepinephrine from the synaptic cleft and acts variably as a serotonin receptor agonist (5-HT1A), partial agonist (5-HT1B) or antagonist (5-HT3, 5-HT1D and 5-HT7). It is not clear how this agent's purported multimodal mechanism of action contributes to its antidepressant effect; however, it is presumed to increase the synaptic availability of serotonin and norepinephrine.

ID

http://purl.obolibrary.org/obo/NCIT_C125653

CAS_Registry

960203-27-4

code

C125653

Contributing_Source

FDA

definition

A hydrobromide salt form of vortioxetine, a serotonin (5-HT) modulator and stimulator (SMS), with antidepressant activity. Vortioxetine inhibits the reuptake of serotonin and norepinephrine from the synaptic cleft and acts variably as a serotonin receptor agonist (5-HT1A), partial agonist (5-HT1B) or antagonist (5-HT3, 5-HT1D and 5-HT7). It is not clear how this agent's purported multimodal mechanism of action contributes to its antidepressant effect; however, it is presumed to increase the synaptic availability of serotonin and norepinephrine.

FDA_UNII_Code

TKS641KOAY

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

http://purl.obolibrary.org/obo/NCIT_C176424

label

Vortioxetine Hydrobromide

NCI_Drug_Dictionary_ID

778329

PDQ_Closed_Trial_Search_ID

778329

PDQ_Open_Trial_Search_ID

778329

Preferred_Name

Vortioxetine Hydrobromide

prefixIRI

NCIT:C125653

prefLabel

Vortioxetine Hydrobromide

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C3667599

subClassOf

http://purl.obolibrary.org/obo/NCIT_C265

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