loading...| Preferred Name |
Tropisetron |
|
| Synonyms |
|
|
| Definitions |
An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy-and radiotherapy-induced nausea and vomiting. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1131 |
|
| Accepted_Therapeutic_Use_For |
Chemotherapy-induced nausea and vomiting |
|
| ALT_DEFINITION |
A substance used to treat nausea and vomiting caused by cancer treatment. It is not available in the United States. Tropisetron is a type of serotonin receptor antagonist and a type of antiemetic. |
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| CAS_Registry |
89565-68-4 |
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| Chemical_Formula |
C17H20N2O2 |
|
| code |
C1131 |
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| Contributing_Source |
CTRP FDA |
|
| definition |
An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy-and radiotherapy-induced nausea and vomiting. (NCI04) |
|
| Display_Name |
Tropisetron |
|
| FDA_UNII_Code |
6I819NIK1W |
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| Has_Salt_Form | ||
| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Tropisetron |
|
| Legacy Concept Name |
Tropisetron |
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| NCI_Drug_Dictionary_ID |
43507 |
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| PDQ_Closed_Trial_Search_ID |
43507 |
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| PDQ_Open_Trial_Search_ID |
43507 |
|
| Preferred_Name |
Tropisetron |
|
| prefixIRI |
NCIT:C1131 |
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| prefLabel |
Tropisetron |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0063322 |
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| subClassOf |