Preferred Name |
Ondansetron |
|
Synonyms |
|
|
Definitions |
A carbazole derivative with antiemetic activity. As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. (NCI04) |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C1119 |
|
Accepted_Therapeutic_Use_For |
Nausea and vomiting prophylaxis, chemotherapy-induced and postoperative |
|
ALT_DEFINITION |
The active ingredient in a drug used to treat nausea and vomiting caused by cancer treatment. Ondansetron is a type of serotonin receptor antagonist and a type of antiemetic. |
|
CAS_Registry |
116002-70-1 99614-02-5 |
|
Chemical_Formula |
C18H19N3O |
|
code |
C1119 |
|
Contributing_Source |
CTRP FDA |
|
definition |
A carbazole derivative with antiemetic activity. As a selective serotonin receptor antagonist, ondansetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. (NCI04) |
|
Display_Name |
Ondansetron |
|
FDA_UNII_Code |
4AF302ESOS |
|
Has_Salt_Form | ||
Has_Target | ||
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
label |
Ondansetron |
|
Legacy Concept Name |
Ondansetron |
|
NCI_Drug_Dictionary_ID |
40693 |
|
PDQ_Closed_Trial_Search_ID |
40693 |
|
PDQ_Open_Trial_Search_ID |
40693 |
|
Preferred_Name |
Ondansetron |
|
prefixIRI |
NCIT:C1119 |
|
prefLabel |
Ondansetron |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0061851 |
|
subClassOf |