Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
Jump to:
| Preferred Name | Arylsulfatase A | |
| Synonyms |
|
|
| Definitions |
Arylsulfatase A (507 aa, ~54 kDa) is encoded by the human ARSA gene. This protein is involved in the hydrolysis of cerebroside sulfate. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C103932 |
|
| code |
C103932
|
|
| Contributing_Source |
CTRP
|
|
| definition |
Arylsulfatase A (507 aa, ~54 kDa) is encoded by the human ARSA gene. This protein is involved in the hydrolysis of cerebroside sulfate.
|
|
| DesignNote |
Mutation of the SUMF1 gene results in misprocessing of arylsulfatase A and all other sulfatases leading to multiple sulfatase deficiency. (UniProt) The conversion of a cysteine residue in eukaryotes to 3-oxoalanine (also known as C-formylglycine, FGly), is critical for catalytic activity. (UniProt)
|
|
| Display_Name |
Arylsulfatase A
|
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
|
| label |
Arylsulfatase A
|
|
| OMIM_Number |
607574
|
|
| Preferred_Name |
Arylsulfatase A
|
|
| prefixIRI |
NCIT:C103932
|
|
| prefLabel |
Arylsulfatase A
|
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme
|
|
| Swiss_Prot |
P15289
|
|
| UMLS_CUI |
C0007804
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping