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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Lipegfilgrastim | |
| Synonyms |
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| Definitions |
A long acting glyco-pegylated recombinant form of human granulocyte colony-stimulating factor (G-CSF), with hematopoietic activity. Similar to G-CSF, lipegfilgrastim binds to and activates specific cell surface receptors, and stimulates neutrophil progenitor proliferation and differentiation. Therefore, this agent may prevent the duration and incidence of chemotherapy-induced neutropenia. Compared to filgrastim, lipegfilgrastim has a prolonged plasma half-life. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C101778 |
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| CAS_Registry |
1117844-87-7
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| code |
C101778
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| Contributing_Source |
CTRP FDA
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|
| definition |
A long acting glyco-pegylated recombinant form of human granulocyte colony-stimulating factor (G-CSF), with hematopoietic activity. Similar to G-CSF, lipegfilgrastim binds to and activates specific cell surface receptors, and stimulates neutrophil progenitor proliferation and differentiation. Therefore, this agent may prevent the duration and incidence of chemotherapy-induced neutropenia. Compared to filgrastim, lipegfilgrastim has a prolonged plasma half-life.
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| Display_Name |
Lipegfilgrastim
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| FDA_UNII_Code |
4AWF0N6QV3
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
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| label |
Lipegfilgrastim
|
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| NCI_Drug_Dictionary_ID |
732856
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| PDQ_Closed_Trial_Search_ID |
732856
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| PDQ_Open_Trial_Search_ID |
732856
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| Preferred_Name |
Lipegfilgrastim
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|
| prefixIRI |
NCIT:C101778
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| prefLabel |
Lipegfilgrastim
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| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance
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| UMLS_CUI |
C3640212
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| subClassOf |
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