loading...| Preferred Name | Verteporfin | |
| Synonyms |
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|
| Definitions |
A synthetic light-activated agent with photodynamic activity. Upon systemic administration, verteporfin accumulates in neovessels in the eye and, once stimulated by nonthermal red light in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to neovascular endothelium and blood vessel occlusion. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1014 |
|
| Accepted_Therapeutic_Use_For |
Photosensitizer, subfoveal choroidal neovascularization |
|
| CAS_Registry |
129497-78-5 |
|
| CHEBI_ID |
CHEBI:32293 |
|
| code |
C1014 |
|
| Contributing_Source |
FDA |
|
| definition |
A synthetic light-activated agent with photodynamic activity. Upon systemic administration, verteporfin accumulates in neovessels in the eye and, once stimulated by nonthermal red light in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to neovascular endothelium and blood vessel occlusion. (NCI04) |
|
| FDA_UNII_Code |
0X9PA28K43 |
|
| in_subset | ||
| label |
Verteporfin |
|
| Legacy Concept Name |
Verteporfin |
|
| NCI_Drug_Dictionary_ID |
42130 |
|
| PDQ_Closed_Trial_Search_ID |
42130 |
|
| PDQ_Open_Trial_Search_ID |
42130 |
|
| Preferred_Name |
Verteporfin |
|
| prefixIRI |
NCIT:C1014 |
|
| prefLabel |
Verteporfin |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance Biologically Active Substance |
|
| UMLS_CUI |
C0387288 |
|
| subClassOf |