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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | tolazamide | |
| Synonyms |
4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide tolazamidum N-{[(hexahydro-1H-azepin-1-yl)-amino]carbonyl}-4-methylbenzenesulfonamide EINECS 214-588-3 1-(hexahydro-1-azepinyl)-3-p-tolylsulfonylurea N-(p-toluenesulfonyl)-N'-hexamethyleniminourea BRN 1323565 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea CCRIS 591 Diabewas Norglycin Tolinase U 17835 U-17835 tolazamida tolazamide N-(azepan-1-ylcarbamoyl)-4-methylbenzenesulfonamide |
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| Definitions |
An N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_9613 |
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| alternative term |
4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide tolazamidum N-{[(hexahydro-1H-azepin-1-yl)-amino]carbonyl}-4-methylbenzenesulfonamide EINECS 214-588-3 1-(hexahydro-1-azepinyl)-3-p-tolylsulfonylurea N-(p-toluenesulfonyl)-N'-hexamethyleniminourea BRN 1323565 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea CCRIS 591 Diabewas Norglycin Tolinase U 17835 U-17835 tolazamida tolazamide N-(azepan-1-ylcarbamoyl)-4-methylbenzenesulfonamide
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|
| bearer of | ||
| charge |
0
|
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| database_cross_reference |
PMID:15901207 HMDB:HMDB0014977 PMID:8237731 Drug_Central:2694 CAS:1156-19-0 KEGG:D00379 Patent:GB887886 LINCS:LSM-2699 Reaxys:1323565 Wikipedia:Tolazamide DrugBank:DB00839
|
|
| definition |
An N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus.
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|
| formula |
C14H21N3O3S
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|
| has_exact_synonym |
N-(azepan-1-ylcarbamoyl)-4-methylbenzenesulfonamide
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|
| has_obo_namespace |
chebi_ontology
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| has_related_synonym |
4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide tolazamidum N-{[(hexahydro-1H-azepin-1-yl)-amino]carbonyl}-4-methylbenzenesulfonamide EINECS 214-588-3 1-(hexahydro-1-azepinyl)-3-p-tolylsulfonylurea N-(p-toluenesulfonyl)-N'-hexamethyleniminourea BRN 1323565 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea CCRIS 591 Diabewas Norglycin Tolinase U 17835 U-17835 tolazamida tolazamide
|
|
| id |
CHEBI:9613
|
|
| in_subset | ||
| inchi |
InChI=1S/C14H21N3O3S/c1-12-6-8-13(9-7-12)21(19,20)16-14(18)15-17-10-4-2-3-5-11-17/h6-9H,2-5,10-11H2,1H3,(H2,15,16,18)
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|
| inchikey |
OUDSBRTVNLOZBN-UHFFFAOYSA-N
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|
| label |
tolazamide
|
|
| mass |
311.40000
|
|
| monoisotopicmass |
311.13036
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| notation |
CHEBI:9613
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|
| prefLabel |
tolazamide
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|
| RO_0000087 | ||
| smiles |
Cc1ccc(cc1)S(=O)(=O)NC(=O)NN1CCCCCC1
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| subClassOf |
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