loading...| Preferred Name | megestrol acetate | |
| Synonyms |
6-methyl-delta(sup 4,6)-pregnadien-17alpha-ol-3,20-dione acetate 6-methyl-delta(sup 6)-dehydro-17alpha-acetoxyprogesterone 17-acetoxy-6-methylpregna-4,6-diene-3,20-dione 17alpha-acetoxy-6-dehydro-6-methylprogesterone 6-methyl-17alpha-acetoxypregna-4,6-diene-3,20-dione 6-dehydro-6-methyl-17alpha-acetoxyprogesterone 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate 17alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate 6-methyl-6-dehydro-17alpha-acetoxyprogesterone 6-methyl-17alpha-hydroxy-delta(sup 6)-progesterone acetate BDH 1298 BDH-1298 BDH1298 Maygace Megace Megeron Megestat Megestil Megestin Niagestin Ovaban Ovarid Pallace SC 10363 SC-10363 SC10363 Volidan magestin 6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate |
|
| Definitions |
A steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_6723 |
|
| alternative term |
6-methyl-delta(sup 4,6)-pregnadien-17alpha-ol-3,20-dione acetate 6-methyl-delta(sup 6)-dehydro-17alpha-acetoxyprogesterone 17-acetoxy-6-methylpregna-4,6-diene-3,20-dione 17alpha-acetoxy-6-dehydro-6-methylprogesterone 6-methyl-17alpha-acetoxypregna-4,6-diene-3,20-dione 6-dehydro-6-methyl-17alpha-acetoxyprogesterone 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate 17alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate 6-methyl-6-dehydro-17alpha-acetoxyprogesterone 6-methyl-17alpha-hydroxy-delta(sup 6)-progesterone acetate BDH 1298 BDH-1298 BDH1298 Maygace Megace Megeron Megestat Megestil Megestin Niagestin Ovaban Ovarid Pallace SC 10363 SC-10363 SC10363 Volidan magestin 6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate |
|
| bearer of |
http://purl.obolibrary.org/obo/CHEBI_50779 http://purl.obolibrary.org/obo/CHEBI_35610 |
|
| charge |
0 |
|
| database_cross_reference |
Patent:US3356573 PMID:31359357 PMID:29442239 PMID:31497435 Patent:US3400137 Patent:GB870286 PMID:27038209 Patent:US2891079 PMID:29542279 Wikipedia:Megestrol_acetate PMID:29095656 PMID:29050522 KEGG:D00952 PMCID:PMC7207385 KEGG:C08151 LIPID_MAPS_instance:LMST02030118 PMID:32652300 DrugBank:DB00351 PMID:5320316 CAS:595-33-5 PMID:27639080 PMID:32122805 PMID:28986550 PMID:30157059 PMID:29581752 PMID:32084501 PMID:31451262 PMID:27218795 PMID:31462353 PMID:31961463 PMID:29400904 PMID:11986264 Beilstein:1917291 PMID:31036192 PMID:30112227 |
|
| definition |
A steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer. |
|
| formula |
C24H32O4 |
|
| has_exact_synonym |
6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate |
|
| has_functional_parent | ||
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
6-methyl-delta(sup 4,6)-pregnadien-17alpha-ol-3,20-dione acetate 6-methyl-delta(sup 6)-dehydro-17alpha-acetoxyprogesterone 17-acetoxy-6-methylpregna-4,6-diene-3,20-dione 17alpha-acetoxy-6-dehydro-6-methylprogesterone 6-methyl-17alpha-acetoxypregna-4,6-diene-3,20-dione 6-dehydro-6-methyl-17alpha-acetoxyprogesterone 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate 17alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate 6-methyl-6-dehydro-17alpha-acetoxyprogesterone 6-methyl-17alpha-hydroxy-delta(sup 6)-progesterone acetate BDH 1298 BDH-1298 BDH1298 Maygace Megace Megeron Megestat Megestil Megestin Niagestin Ovaban Ovarid Pallace SC 10363 SC-10363 SC10363 Volidan magestin |
|
| id |
CHEBI:6723 |
|
| in_subset | ||
| inchi |
InChI=1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1 |
|
| inchikey |
RQZAXGRLVPAYTJ-GQFGMJRRSA-N |
|
| label |
megestrol acetate |
|
| mass |
370.48190 |
|
| monoisotopicmass |
370.21441 |
|
| notation |
CHEBI:6723 |
|
| prefLabel |
megestrol acetate |
|
| RO_0000087 |
http://purl.obolibrary.org/obo/CHEBI_50779 http://purl.obolibrary.org/obo/CHEBI_35610 |
|
| smiles |
[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=C(C)C2=CC(=O)CC[C@]12C |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_47880 http://purl.obolibrary.org/obo/CHEBI_47622 |