loading...| Preferred Name | maytansine | |
| Synonyms |
maitansinum NSC 153858 NSC-153858 maitansina maitansine (4beta,5beta,11E,13E)-maytansine Maytansine |
|
| Definitions |
An organic heterotetracyclic compound and 19-membered macrocyclic lactam antibiotic originally isolated from the Ethiopian shrub Maytenus serrata but also found in other Maytenus species. It exhibits cytotoxicity against many tumour cell lines. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_6701 |
|
| alternative term |
maitansinum NSC 153858 NSC-153858 maitansina maitansine (4beta,5beta,11E,13E)-maytansine Maytansine |
|
| bearer of |
http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_76924 http://purl.obolibrary.org/obo/CHEBI_33281 |
|
| charge |
0 |
|
| database_cross_reference |
Wikipedia:Maytansine KEGG:C10606 PMID:20937594 PMID:1241159 PMID:3834790 LIPID_MAPS_instance:LMPK04000017 KNApSAcK:C00002351 PMID:628025 Reaxys:5417399 CAS:35846-53-8 KEGG:D04864 PMID:367597 |
|
| definition |
An organic heterotetracyclic compound and 19-membered macrocyclic lactam antibiotic originally isolated from the Ethiopian shrub Maytenus serrata but also found in other Maytenus species. It exhibits cytotoxicity against many tumour cell lines. |
|
| formula |
C34H46ClN3O10 |
|
| has_exact_synonym |
(4beta,5beta,11E,13E)-maytansine Maytansine |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
maitansinum NSC 153858 NSC-153858 maitansina maitansine |
|
| id |
CHEBI:6701 |
|
| in_subset | ||
| inchi |
InChI=1S/C34H46ClN3O10/c1-18-11-10-12-26(45-9)34(43)17-25(46-32(42)36-34)19(2)30-33(5,48-30)27(47-31(41)20(3)37(6)21(4)39)16-28(40)38(7)23-14-22(13-18)15-24(44-8)29(23)35/h10-12,14-15,19-20,25-27,30,43H,13,16-17H2,1-9H3,(H,36,42)/b12-10+,18-11+/t19-,20+,25+,26-,27+,30+,33+,34+/m1/s1 |
|
| inchikey |
WKPWGQKGSOKKOO-RSFHAFMBSA-N |
|
| label |
maytansine |
|
| mass |
692.19600 |
|
| monoisotopicmass |
691.28717 |
|
| notation |
CHEBI:6701 |
|
| prefLabel |
maytansine |
|
| RO_0000087 |
http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_76924 http://purl.obolibrary.org/obo/CHEBI_33281 |
|
| smiles |
CO[C@@H]1\C=C\C=C(C)\Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(C)=O)[C@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_46874 http://purl.obolibrary.org/obo/CHEBI_32955 http://purl.obolibrary.org/obo/CHEBI_36683 http://purl.obolibrary.org/obo/CHEBI_23003 |