Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
Jump to:
| Preferred Name | lenalidomide | |
| Synonyms |
lenalidomide 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline Revlimid 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione |
|
| Definitions |
A dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_63791 |
|
| alternative term |
lenalidomide 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline Revlimid 3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
|
|
| bearer of |
http://purl.obolibrary.org/obo/CHEBI_35610 |
|
| charge |
0
|
|
| database_cross_reference |
PMID:21533608 Reaxys:8335210 PMID:22246035 PMID:22211836 Wikipedia:Lenalidomide PMID:21823830 Drug_Central:3317 PMID:22245427 KEGG:D04687 PMID:21835953 PMID:22245805 PMID:22245806 PMID:22261445 PMID:22241792 PMID:22001752 CAS:191732-72-6 PMID:22253550 PMID:22107129 LINCS:LSM-6187 PMID:22066855 PMID:22143062 DrugBank:DB00480
|
|
| definition |
A dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha.
|
|
| formula |
C13H13N3O3
|
|
| has_exact_synonym |
3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
lenalidomide 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline Revlimid
|
|
| id |
CHEBI:63791
|
|
| in_subset | ||
| inchi |
InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
|
|
| inchikey |
GOTYRUGSSMKFNF-UHFFFAOYSA-N
|
|
| label |
lenalidomide
|
|
| mass |
259.26060
|
|
| monoisotopicmass |
259.09569
|
|
| notation |
CHEBI:63791
|
|
| prefLabel |
lenalidomide
|
|
| RO_0000087 |
http://purl.obolibrary.org/obo/CHEBI_35610 |
|
| smiles |
Nc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O
|
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_33860 http://purl.obolibrary.org/obo/CHEBI_24897 |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping