loading...| Preferred Name | hydroxychloroquine | |
| Synonyms |
7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline oxichloroquine 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline hydroxychloroquine (+-)-hydroxychloroquine Polirreumin 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol 7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline hidroxicloroquina 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline hydroxychloroquinum oxichlorochine 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol NSC4375 2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol |
|
| Definitions |
An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_5801 |
|
| alternative term |
7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline oxichloroquine 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline hydroxychloroquine (+-)-hydroxychloroquine Polirreumin 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol 7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline hidroxicloroquina 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline hydroxychloroquinum oxichlorochine 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol NSC4375 2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol |
|
| bearer of |
http://purl.obolibrary.org/obo/CHEBI_149553 http://purl.obolibrary.org/obo/CHEBI_50177 |
|
| charge |
0 |
|
| database_cross_reference |
DrugBank:DB01611 KEGG:C07043 HMDB:HMDB0015549 PMID:32295814 KEGG:D08050 PMID:23485647 PMID:32294807 PMCID:PMC7122276 PMID:32215614 PMID:23481418 PMID:23218706 PMID:32283236 CAS:118-42-3 PMID:32269046 Drug_Central:1395 Wikipedia:Hydroxychloroquine PMID:32311324 Reaxys:253894 PMID:23216212 LINCS:LSM-5193 PMID:23902281 Patent:US2546658 PMID:23778483 PMID:23887202 PMID:32295788 PMID:23581274 PMID:32327429 |
|
| definition |
An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions. |
|
| formula |
C18H26ClN3O |
|
| has_exact_synonym |
2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol |
|
| has_functional_parent | ||
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
7-chloro-4-(4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino)quinoline oxichloroquine 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline hydroxychloroquine (+-)-hydroxychloroquine Polirreumin 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol 7-chloro-4-[4-(N-ethyl-N-beta-hydroxyethylamino)-1-methylbutylamino]quinoline hidroxicloroquina 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline hydroxychloroquinum oxichlorochine 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol NSC4375 |
|
| id |
CHEBI:5801 |
|
| in_subset | ||
| inchi |
InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21) |
|
| inchikey |
XXSMGPRMXLTPCZ-UHFFFAOYSA-N |
|
| is_conjugate_base_of | ||
| label |
hydroxychloroquine |
|
| mass |
335.87200 |
|
| monoisotopicmass |
335.17644 |
|
| notation |
CHEBI:5801 |
|
| prefLabel |
hydroxychloroquine |
|
| RO_0000087 |
http://purl.obolibrary.org/obo/CHEBI_149553 http://purl.obolibrary.org/obo/CHEBI_50177 |
|
| smiles |
CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_50995 http://purl.obolibrary.org/obo/CHEBI_36709 http://purl.obolibrary.org/obo/CHEBI_36683 |