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Biological and Environmental Research Ontology
| Preferred Name | cyproterone acetate | |
| Synonyms |
17alpha-acetoxy-6-chloro-1alpha,2alpha-methylenepregna-4,6-diene-3,20-dione (1beta,2beta)-17-(acetyloxy)-6-chloro-1,2-dihydro-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione acetic acid (8R,9S,10S,13S,14S,17R)-17-acetyl-6-(S)-chloro-10,13-dimethyl-3-(R)-oxo-1,2,3,8,9,10,11,12,13,14,15,16,17,20-tetradecahydro-cyclopropa[1,2]cyclopenta[a]phenanthren-17-yl ester (1R,3aS,3bR,7aR,8aS,8bS,8cS,10aS)-1-acetyl-5-chloro-8b,10a-dimethyl-7-oxo-1,2,3,3a,3b,7,7a,8,8a,8b,8c,9,10,10a-tetradecahydrocyclopenta[a]cyclopropa[g]phenanthren-1-yl acetate cyproterone 17alpha-acetate 1,2alpha-methylene-6-chloro-17alpha-acetoxy-4,6-pregnadiene-3,20-dione 6-chloro-1,2alpha-methylene-6-dehydro-17alpha-hydroxyprogesterone acetate 6-chloro-1,2alpha-methylene-17alpha-hydroxy-Delta(6)-progesterone acetate 1,2alpha-methylene-6-chloro-Delta(4,6)-pregnadien-17alpha-ol-3,20-dione acetate 6-chloro-17-hydroxy-1alpha,2alpha-methylenepregna-4,6-diene-3,20-dione acetate Cyproterone 17-O-acetate 1,2alpha-methylene-6-chloro-pregna-4,6-diene-3,20-dione 17alpha-acetate Androcur Cyprostat SH 714 CYPROTERONE ACETATE 6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclopropa[1,2]pregna-4,6-dien-17-yl acetate |
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| Definitions |
A steroid ester resulting from the formal condensation of the carboxy group of acetic acid with the 17-hydroxy group of cyproterone. It is an antiandrogenic drug which has recently been recognized to promote the occurrence and growth of intracranial meningiomas. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_50743 |
|
| alternative term |
17alpha-acetoxy-6-chloro-1alpha,2alpha-methylenepregna-4,6-diene-3,20-dione (1beta,2beta)-17-(acetyloxy)-6-chloro-1,2-dihydro-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione acetic acid (8R,9S,10S,13S,14S,17R)-17-acetyl-6-(S)-chloro-10,13-dimethyl-3-(R)-oxo-1,2,3,8,9,10,11,12,13,14,15,16,17,20-tetradecahydro-cyclopropa[1,2]cyclopenta[a]phenanthren-17-yl ester (1R,3aS,3bR,7aR,8aS,8bS,8cS,10aS)-1-acetyl-5-chloro-8b,10a-dimethyl-7-oxo-1,2,3,3a,3b,7,7a,8,8a,8b,8c,9,10,10a-tetradecahydrocyclopenta[a]cyclopropa[g]phenanthren-1-yl acetate cyproterone 17alpha-acetate 1,2alpha-methylene-6-chloro-17alpha-acetoxy-4,6-pregnadiene-3,20-dione 6-chloro-1,2alpha-methylene-6-dehydro-17alpha-hydroxyprogesterone acetate 6-chloro-1,2alpha-methylene-17alpha-hydroxy-Delta(6)-progesterone acetate 1,2alpha-methylene-6-chloro-Delta(4,6)-pregnadien-17alpha-ol-3,20-dione acetate 6-chloro-17-hydroxy-1alpha,2alpha-methylenepregna-4,6-diene-3,20-dione acetate Cyproterone 17-O-acetate 1,2alpha-methylene-6-chloro-pregna-4,6-diene-3,20-dione 17alpha-acetate Androcur Cyprostat SH 714 CYPROTERONE ACETATE 6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclopropa[1,2]pregna-4,6-dien-17-yl acetate
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| bearer of |
http://purl.obolibrary.org/obo/CHEBI_35497 |
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| charge |
0
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| database_cross_reference |
PMID:33081822 PMID:11393581 Beilstein:2342172 PMID:32418729 DrugBank:DB04839 CAS:427-51-0 PMID:34176757 PMID:14583927 PMID:33989640 PDBeChem:CA4 PMID:34125226 PMID:31634588 PMCID:PMC7208009 PMID:16372511 PMID:17311914 PMID:31197615 PMID:33392938 Wikipedia:Cyproterone_Acetate PMID:34187864 PMID:33536184 PMID:34196865 PMID:30666456 PMID:24134630 Drug_Central:766 KEGG:D01368 PMID:33394263 Patent:DE1189991 PMID:31815317 PMID:15063071 Patent:US3234093 PMID:17167851 Chemspider:9496 PMID:33055297 PMID:34274044 PMID:11551428 PMID:33750846 PMID:34592677 PMID:34613529
|
|
| definition |
A steroid ester resulting from the formal condensation of the carboxy group of acetic acid with the 17-hydroxy group of cyproterone. It is an antiandrogenic drug which has recently been recognized to promote the occurrence and growth of intracranial meningiomas.
|
|
| formula |
C24H29ClO4
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|
| has_alternative_id |
CHEBI:31451 CHEBI:47297 CHEBI:336019
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|
| has_exact_synonym |
CYPROTERONE ACETATE 6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclopropa[1,2]pregna-4,6-dien-17-yl acetate
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| has_functional_parent | ||
| has_obo_namespace |
chebi_ontology
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| has_related_synonym |
17alpha-acetoxy-6-chloro-1alpha,2alpha-methylenepregna-4,6-diene-3,20-dione (1beta,2beta)-17-(acetyloxy)-6-chloro-1,2-dihydro-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione acetic acid (8R,9S,10S,13S,14S,17R)-17-acetyl-6-(S)-chloro-10,13-dimethyl-3-(R)-oxo-1,2,3,8,9,10,11,12,13,14,15,16,17,20-tetradecahydro-cyclopropa[1,2]cyclopenta[a]phenanthren-17-yl ester (1R,3aS,3bR,7aR,8aS,8bS,8cS,10aS)-1-acetyl-5-chloro-8b,10a-dimethyl-7-oxo-1,2,3,3a,3b,7,7a,8,8a,8b,8c,9,10,10a-tetradecahydrocyclopenta[a]cyclopropa[g]phenanthren-1-yl acetate cyproterone 17alpha-acetate 1,2alpha-methylene-6-chloro-17alpha-acetoxy-4,6-pregnadiene-3,20-dione 6-chloro-1,2alpha-methylene-6-dehydro-17alpha-hydroxyprogesterone acetate 6-chloro-1,2alpha-methylene-17alpha-hydroxy-Delta(6)-progesterone acetate 1,2alpha-methylene-6-chloro-Delta(4,6)-pregnadien-17alpha-ol-3,20-dione acetate 6-chloro-17-hydroxy-1alpha,2alpha-methylenepregna-4,6-diene-3,20-dione acetate Cyproterone 17-O-acetate 1,2alpha-methylene-6-chloro-pregna-4,6-diene-3,20-dione 17alpha-acetate Androcur Cyprostat SH 714
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|
| id |
CHEBI:50743
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| in_subset | ||
| inchi |
InChI=1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17-,18-,22-,23-,24-/m0/s1
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| inchikey |
UWFYSQMTEOIJJG-FDTZYFLXSA-N
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| label |
cyproterone acetate
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|
| mass |
416.940
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|
| monoisotopicmass |
416.17544
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|
| notation |
CHEBI:50743
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| prefLabel |
cyproterone acetate
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| RO_0000087 |
http://purl.obolibrary.org/obo/CHEBI_35497 |
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| smiles |
[H][C@@]12C[C@]1([H])[C@@]1(C)C(=CC2=O)C(Cl)=C[C@@]2([H])[C@]3([H])CC[C@](OC(C)=O)(C(C)=O)[C@@]3(C)CC[C@]12[H]
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| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_47880 http://purl.obolibrary.org/obo/CHEBI_47622 http://purl.obolibrary.org/obo/CHEBI_77175 |
| Delete | Subject | Author | Type | Created |
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