Link to this page
Biological and Environmental Research Ontology
| Preferred Name | esmolol | |
| Synonyms |
(+-)-esmolol 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate (+-)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate esmolol esmololum rac-methyl 3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoate ESMOLOL Esmolol |
|
| Definitions |
A racemate comprising equimolar amounts of (R)- and (S)-esmolol. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used as the hydrochloride salt in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery. While the S enantiomer possesses all of the heart rate control, both enantiomers contribute to lowering blood pressure. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4856 |
|
| alternative term |
(+-)-esmolol 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate (+-)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate esmolol esmololum rac-methyl 3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoate ESMOLOL Esmolol
|
|
| bearer of | ||
| charge |
0
|
|
| database_cross_reference |
Patent:EP41491 PMID:24500140 CAS:103598-03-4 CAS:81147-92-4 KEGG:D07916 PMID:26316443 Reaxys:5287174 Patent:EP53435 PMID:16118074 PMID:25105423 PMID:25575405 Patent:US4593119 Wikipedia:Esmolol KEGG:C06980 HMDB:HMDB0014333 PMID:26137757 DrugBank:DB00187 PMID:26073350 Beilstein:5287174
|
|
| definition |
A racemate comprising equimolar amounts of (R)- and (S)-esmolol. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used as the hydrochloride salt in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery. While the S enantiomer possesses all of the heart rate control, both enantiomers contribute to lowering blood pressure.
|
|
| formula |
C16H25NO4
|
|
| has part | ||
| has_alternative_id |
CHEBI:143354
|
|
| has_exact_synonym |
rac-methyl 3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoate ESMOLOL Esmolol
|
|
| has_functional_parent | ||
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
(+-)-esmolol 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate (+-)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate esmolol esmololum
|
|
| id |
CHEBI:4856
|
|
| in_subset | ||
| label |
esmolol
|
|
| mass |
295.375
|
|
| monoisotopicmass |
295.17836
|
|
| notation |
CHEBI:4856
|
|
| overlaps | ||
| prefLabel |
esmolol
|
|
| RO_0000087 | ||
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |