loading...| Preferred Name |
colistimethate sodium |
|
| Synonyms |
Colistimethate sodium colistin sulfomethate sodium colistin sulfomethate sodium colistin methanesulfonate sodium colistinemethanesulfonate colistimethate sodium Colistin methanesulfonate pentasodium colistinmethanesulfonate sodium colistimethate colistimethate Colistin sodium methanesulfonate |
|
| Definitions |
A mixture where R = H or Me. Colistin in which each of the primary amino groups is converted to the corresponding aminomethanesulfonic acid sodium salt, commonly by the action of formaldehyde followed by sodium bisulfite. A polymyxin antibiotic derivative, it is used in the treatment of severe infections, particularly of multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_34650 |
|
| charge |
0 |
|
| database_cross_reference |
KEGG:C13553 CAS:8068-28-8 DrugBank:DB01111 KEGG:D02049 PMID:18625681 PMID:16931410 |
|
| definition |
A mixture where R = H or Me. Colistin in which each of the primary amino groups is converted to the corresponding aminomethanesulfonic acid sodium salt, commonly by the action of formaldehyde followed by sodium bisulfite. A polymyxin antibiotic derivative, it is used in the treatment of severe infections, particularly of multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii. |
|
| formula |
C57H102N16Na5O28S5R |
|
| has part |
http://purl.obolibrary.org/obo/CHEBI_59663 |
|
| has_alternative_id |
CHEBI:597110 |
|
| has_exact_synonym |
Colistimethate sodium |
|
| has_functional_parent | ||
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
colistin sulfomethate sodium colistin sulfomethate sodium colistin methanesulfonate sodium colistinemethanesulfonate colistimethate sodium Colistin methanesulfonate pentasodium colistinmethanesulfonate sodium colistimethate colistimethate Colistin sodium methanesulfonate |
|
| id |
CHEBI:34650 |
|
| in_subset | ||
| label |
colistimethate sodium |
|
| mass |
1734.792 |
|
| monoisotopicmass |
1733.51415 |
|
| notation |
CHEBI:34650 |
|
| prefLabel |
colistimethate sodium |
|
| RO_0000087 | ||
| smiles |
C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]1C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)NCC1)[C@@H](C)O)=O)CCNCS([O-])(=O)=O)=O)CCNCS([O-])(=O)=O)=O)CC(C)C)=O)CC(C)C)=O)CCNCS([O-])(=O)=O)=O)=O)CCNCS([O-])(=O)=O)=O)[C@@H](C)O)=O)CCNCS([O-])(=O)=O)=O)CCC[C@@H](C*)C.[Na+].[Na+].[Na+].[Na+].[Na+] |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_38700 |