loading...| Preferred Name |
fluorometholone |
|
| Synonyms |
9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione (6alpha,11beta)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione fluorometholonum 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione Fluorometholon fluorometholone fluorometolona Fluor-op NSC 33001 Oxylone |
|
| Definitions |
A member of the class of glucocorticoids that is Delta(1)-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_31625 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:23865053 PMID:24074291 Reaxys:3172388 Drug_Central:1208 Wikipedia:Fluorometholone PMID:22821643 HMDB:HMDB0014469 PMID:24227962 PMID:23023407 PMID:24493163 KEGG:D01367 DrugBank:DB00324 PMID:23225837 PMID:23429038 CAS:426-13-1 |
|
| definition |
A member of the class of glucocorticoids that is Delta(1)-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe. |
|
| formula |
C22H29FO4 |
|
| has_exact_synonym |
9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione (6alpha,11beta)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione |
|
| has_functional_parent | ||
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
fluorometholonum 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione Fluorometholon fluorometholone fluorometolona Fluor-op NSC 33001 Oxylone |
|
| id |
CHEBI:31625 |
|
| in_subset | ||
| inchi |
InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1 |
|
| inchikey |
FAOZLTXFLGPHNG-KNAQIMQKSA-N |
|
| label |
fluorometholone |
|
| mass |
376.46170 |
|
| monoisotopicmass |
376.20499 |
|
| notation |
CHEBI:31625 |
|
| prefLabel |
fluorometholone |
|
| RO_0000087 | ||
| smiles |
C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]2(C)C=CC(=O)C=C12 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_139592 http://purl.obolibrary.org/obo/CHEBI_36885 http://purl.obolibrary.org/obo/CHEBI_24261 http://purl.obolibrary.org/obo/CHEBI_77166 http://purl.obolibrary.org/obo/CHEBI_50830 |