loading...| Preferred Name | 5-aminolevulinic acid | |
| Synonyms |
5-Aminolevulinate delta-aminolevulinic acid aminolevulinic acid 5-Amino-4-oxovaleric acid 5-Amino-4-oxopentanoate 5-ALA dALA delta-ALA 5-amino-4-oxopentanoic acid |
|
| Definitions |
The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_17549 |
|
| alternative term |
5-Aminolevulinate delta-aminolevulinic acid aminolevulinic acid 5-Amino-4-oxovaleric acid 5-Amino-4-oxopentanoate 5-ALA dALA delta-ALA 5-amino-4-oxopentanoic acid |
|
| bearer of |
http://purl.obolibrary.org/obo/CHEBI_47868 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_76924 http://purl.obolibrary.org/obo/CHEBI_75772 http://purl.obolibrary.org/obo/CHEBI_77746 http://purl.obolibrary.org/obo/CHEBI_75771 http://purl.obolibrary.org/obo/CHEBI_76971 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:22700502 PMID:23299429 PMID:15756058 PMID:23307195 PMID:23339045 PMID:19378778 PMID:23242333 LINCS:LSM-5677 PMID:7890117 DrugBank:DB00855 CAS:106-60-5 PMID:11303952 KEGG:C00430 PMID:23291627 HMDB:HMDB0001149 PMID:22378066 PMID:18982627 Wikipedia:Aminolevulinic_acid Reaxys:1759139 KNApSAcK:C00007378 Beilstein:1759139 PMID:15996585 PMID:23360321 Drug_Central:166 KEGG:D07567 |
|
| definition |
The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. |
|
| formula |
C5H9NO3 |
|
| has_alternative_id |
CHEBI:20547 CHEBI:2034 |
|
| has_exact_synonym |
5-amino-4-oxopentanoic acid |
|
| has_functional_parent | ||
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
5-Aminolevulinate delta-aminolevulinic acid aminolevulinic acid 5-Amino-4-oxovaleric acid 5-Amino-4-oxopentanoate 5-ALA dALA delta-ALA |
|
| id |
CHEBI:17549 |
|
| in_subset | ||
| inchi |
InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9) |
|
| inchikey |
ZGXJTSGNIOSYLO-UHFFFAOYSA-N |
|
| is_conjugate_acid_of | ||
| is_conjugate_base_of | ||
| is_tautomer_of | ||
| label |
5-aminolevulinic acid |
|
| mass |
131.12990 |
|
| monoisotopicmass |
131.05824 |
|
| notation |
CHEBI:17549 |
|
| prefLabel |
5-aminolevulinic acid |
|
| RO_0000087 |
http://purl.obolibrary.org/obo/CHEBI_47868 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_76924 http://purl.obolibrary.org/obo/CHEBI_75772 http://purl.obolibrary.org/obo/CHEBI_77746 http://purl.obolibrary.org/obo/CHEBI_75771 http://purl.obolibrary.org/obo/CHEBI_76971 |
|
| smiles |
NCC(=O)CCC(O)=O |
|
| subClassOf |