loading...| Preferred Name | fostriecin | |
| Synonyms |
(+)-fostriecin antibiotic CI 920 phosphotrienin fostriecine fostriecina antibiotic CL 1565A (6R)-5,6-dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one fostriecinum CI 920 CI-920 CL 1565A CL-1565A PD 110,161 PD 110161 PD-110,161 fostriecin (1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-1-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate |
|
| Definitions |
A structurally unique, naturally-occurring phosphate monoester isolated from the soil bacterium Streptomyces pulveraceus. It inhibits DNA topoisomerase II as well as several protein phosphatase including PP2A and PPA4, and exhibits potent antitumor activity against several cancer cell lines. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_167004 |
|
| alternative term |
(+)-fostriecin antibiotic CI 920 phosphotrienin fostriecine fostriecina antibiotic CL 1565A (6R)-5,6-dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one fostriecinum CI 920 CI-920 CL 1565A CL-1565A PD 110,161 PD 110161 PD-110,161 fostriecin (1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-1-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate |
|
| bearer of |
http://purl.obolibrary.org/obo/CHEBI_37153 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_156203 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:11457179 PMID:20645347 PMID:31584287 PMID:33184589 PMID:16316259 KNApSAcK:C00018551 PMID:12369868 PMID:28027648 PMID:12489943 PMID:23671329 PMID:20687585 PMID:9738645 PMID:12837094 PMID:23352138 Wikipedia:Fostriecin PMID:19592665 Chemspider:4510160 PMID:23586868 PMID:28090813 PMID:19902969 PMID:12119701 CAS:87810-56-8 |
|
| definition |
A structurally unique, naturally-occurring phosphate monoester isolated from the soil bacterium Streptomyces pulveraceus. It inhibits DNA topoisomerase II as well as several protein phosphatase including PP2A and PPA4, and exhibits potent antitumor activity against several cancer cell lines. |
|
| formula |
C19H27O9P |
|
| has_exact_synonym |
(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-1-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
(+)-fostriecin antibiotic CI 920 phosphotrienin fostriecine fostriecina antibiotic CL 1565A (6R)-5,6-dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one fostriecinum CI 920 CI-920 CL 1565A CL-1565A PD 110,161 PD 110161 PD-110,161 fostriecin |
|
| id |
CHEBI:167004 |
|
| in_subset | ||
| inchi |
InChI=1S/C19H27O9P/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26)/b3-2-,6-4+,8-5-,12-11+/t15-,16+,17+,19+/m0/s1 |
|
| inchikey |
ZMQRJWIYMXZORG-DSWNLJKISA-N |
|
| label |
fostriecin |
|
| mass |
430.390 |
|
| monoisotopicmass |
430.13927 |
|
| notation |
CHEBI:167004 |
|
| prefLabel |
fostriecin |
|
| RO_0000087 |
http://purl.obolibrary.org/obo/CHEBI_37153 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_156203 |
|
| smiles |
C[C@@](O)(\C=C\[C@H]1CC=CC(=O)O1)[C@@H](C[C@@H](O)\C=C/C=C\C=C\CO)OP(O)(O)=O |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_7794 http://purl.obolibrary.org/obo/CHEBI_26188 http://purl.obolibrary.org/obo/CHEBI_134396 http://purl.obolibrary.org/obo/CHEBI_134394 |