Preferred Name |
metformin |
|
Synonyms |
Glucophage |
|
Definitions |
Metformin is a first-line medication for type 2 diabetes. It has been shown to increase Gram-negative membrane permeability and enhance the entry of certain antibiotics, such as tetracyclines, beta-lactams, and rifampicin. Metformin is also able to inhibit antibiotic efflux pumps such as AcrAB-TolC and MdtK. |
|
ID |
http://purl.obolibrary.org/obo/ARO_3007318 |
|
database_cross_reference |
pubchem.compound:4091 |
|
definition |
Metformin is a first-line medication for type 2 diabetes. It has been shown to increase Gram-negative membrane permeability and enhance the entry of certain antibiotics, such as tetracyclines, beta-lactams, and rifampicin. Metformin is also able to inhibit antibiotic efflux pumps such as AcrAB-TolC and MdtK. |
|
has_exact_synonym |
Glucophage |
|
has_obo_namespace |
antibiotic_resistance |
|
id |
ARO:3007318 |
|
label |
metformin |
|
notation |
ARO:3007318 |
|
prefLabel |
metformin |
|
subClassOf |
http://purl.obolibrary.org/obo/ARO_3007328 |