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Antibiotic Resistance Ontology
Last uploaded:
December 18, 2024
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Preferred Name | clofazimine | |
Synonyms |
Lampren Lamprene |
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Definitions |
Clofazimine is a fluoroquinolone-class phenazine dye used for the treatment of leprosy. Clofazimine binds to DNA and disrupts bacterial DNA gyrase, thereby causing double-stranded DNA breaks, and subsequent cell death. |
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ID |
http://purl.obolibrary.org/obo/ARO_3004012 |
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database_cross_reference |
PubChem:2794 CAS:2030-63-9 ChEMBL:CHEMBL1292 ChEBI:3749
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definition |
Clofazimine is a fluoroquinolone-class phenazine dye used for the treatment of leprosy. Clofazimine binds to DNA and disrupts bacterial DNA gyrase, thereby causing double-stranded DNA breaks, and subsequent cell death.
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has_exact_synonym |
Lampren Lamprene
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has_obo_namespace |
antibiotic_resistance
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id |
ARO:3004012
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label |
clofazimine
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notation |
ARO:3004012
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prefLabel |
clofazimine
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subClassOf |
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