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Antibiotic Resistance Ontology
Last uploaded:
December 18, 2024
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| Preferred Name | aztreonam | |
| Synonyms |
AZT Azactam Primbactam |
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| Definitions |
Aztreonam was the first monobactam discovered, and is greatly effective against Gram-negative bacteria while inactive against Gram-positive bacteria. Artreonam is a poor substrate for beta-lactamases, and may even act as an inhibitor. In Gram-negative bacteria, Aztreonam interferes with filamentation, inhibiting cell division and leading to cell death. |
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| ID |
http://purl.obolibrary.org/obo/ARO_3000550 |
|
| database_cross_reference |
PubChem:5742832
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|
| definition |
Aztreonam was the first monobactam discovered, and is greatly effective against Gram-negative bacteria while inactive against Gram-positive bacteria. Artreonam is a poor substrate for beta-lactamases, and may even act as an inhibitor. In Gram-negative bacteria, Aztreonam interferes with filamentation, inhibiting cell division and leading to cell death.
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|
| has_exact_synonym |
AZT Azactam Primbactam
|
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| has_obo_namespace |
antibiotic_resistance
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|
| id |
ARO:3000550
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|
| label |
aztreonam
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|
| notation |
ARO:3000550
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| prefLabel |
aztreonam
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| subClassOf |
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