loading...| Preferred Name | carbenicillin | |
| Synonyms |
Carbenicillina Carbenicilina Microcillin Carbenicillinum Carbenicilline Anabactyl CAR Carbecin Geopen Pyopen |
|
| Definitions |
Carbenicillin is a semi-synthetic antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It has gram-negative coverage which includes Pseudomonas aeruginosa but limited gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes. Carbenicillin antibiotics are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. |
|
| ID |
http://purl.obolibrary.org/obo/ARO_0000043 |
|
| database_cross_reference |
pubchem.compound:20824 |
|
| definition |
Carbenicillin is a semi-synthetic antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It has gram-negative coverage which includes Pseudomonas aeruginosa but limited gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes. Carbenicillin antibiotics are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. |
|
| has_exact_synonym |
Carbenicillina Carbenicilina Microcillin Carbenicillinum Carbenicilline Anabactyl CAR Carbecin Geopen Pyopen |
|
| has_obo_namespace |
antibiotic_resistance |
|
| id |
ARO:0000043 |
|
| label |
carbenicillin |
|
| notation |
ARO:0000043 |
|
| prefLabel |
carbenicillin |
|
| subClassOf |